Google serves up reindeer games with Santa Tracker, lets St. Nick message your besties

Sure, Google's not in the Santa Tracking NORAD cabal anymore, but that's not stopping it from rolling out St. Nicholas-related goodies. It just launched a series of new games, including a chimney / gift dropping challenge, a rocket-powered elf race and a Santa chat that lets you send a droll holiday greeting to your "hoodlum besties." You can even play Rudolph for a lark and drag Santa around in his sleigh -- badly, in our case -- so check the source (hint: click the red box at the bottom left) for some holiday cheer, Mountain View-style.

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Source: Google Santa Tracker

Source: http://www.engadget.com/2012/12/24/google-serves-up-reindeer-games-with-santa-tracker-lets-st-nic/

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Gout study offers genetic insight into 'disease of kings'

Dec. 23, 2012 ? Scientists have shed light on why some people are more susceptible to gout than others. A study has identified 18 new genetic variations that increase levels of uric acid in the blood, which is the main cause of the disease. High levels of uric acid form small crystals in joints and tissues, causing pain and swelling -- the main symptoms of the condition once known as the 'disease of kings'.

Gout is the most common form of inflammatory arthritis, affecting up to two per cent of the world's population. Understanding how these common genetic variants increase uric acid levels in the blood may lead to improvements in the treatment and prevention of the disease. It could also help research into urate-lowering drugs.

The international team of researchers, including scientists from the University of Edinburgh and Queen Mary, University of London, say gout is becoming more common in the developed world.

They attribute its rise in part to increasing levels of obesity and an aging population.

This painful joint inflammation affects at least one in seventy adults in the UK with approximately 900,000 people suffering at least one attack of gout in their lifetime.

The work, published in Nature Genetics, was carried out by analysing the genetic data of more than 140,000 people, from more than 70 individual studies from Europe, the U.S., Japan and Australia and represents the largest study worldwide on this topic.

Dr Veronique Vitart, from the Medical Research Council Human Genetics Unit at the University of Edinburgh, and one of the lead authors of the study said: "Abnormal levels of uric acid have been associated with various common diseases and conditions, but causal relationships are not always clear. Gaining insight into the genetic components of uric acid levels offers a very useful tool to tackle these issues and to further our understanding of these conditions."

Professor Mark Caulfield, from the William Harvey Research Institute at Queen Mary, and a lead author said: "Existing therapies to avoid attacks of gout sometimes cause side effects. Our findings identify new potential mechanisms for gout and offer opportunities for new therapies which may improve prevention of this debilitating condition in the future.

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The above story is reprinted from materials provided by University of Edinburgh, via EurekAlert!, a service of AAAS.

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Journal Reference:

1. K?ttgen et al. Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nature Genetics, 2012; DOI: 10.1038/ng.2500

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/H458lK_NuVE/121223152730.htm

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Cliff Negotiations Take Holiday Break (WSJ)

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In 'fiscal cliff' fight, Obama gets better marks than Boehner

President Obama's approval rating is at a three-year high; Speaker Boehner's is at an all-time low, and a majority of Americans view the GOP as too extreme. Is Boehner's position in danger?

By Brad Knickerbocker,?Staff writer / December 22, 2012

Speaker of the House John Boehner, joined by House Majority Leader Eric Cantor, speaks to reporters about the fiscal cliff negotiations at the Capitol in Washington, Friday.

J. Scott Applewhite/AP

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If you picture the ?fiscal cliff? struggle between the Democratic White House and the Republican House of Representatives as hand-to-hand political combat between the President and Speaker John Boehner, you?d have to score it as advantage Obama by a wide margin.

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Mr. Obama?s approval rating is at a three-year high. Mr. Boehner?s is at an all-time low ? even lower than Nancy Pelosi, the former Speaker Boehner ousted when Republicans took over the House in 2010. Meanwhile, a majority of Americans now say the GOP is too extreme.

Depending on what happens with the automatic tax increases and across-the-board spending cuts that define the fiscal cliff just ten days off, that could change, of course. Public attitudes toward Washington are never very far from ?a pox on both your houses.?

But as the Obama family headed to Hawaii and lawmakers scattered for what?s likely to be a truncated holiday break, the latest polls are a lump of coal in the Republican Christmas stocking.

Recommended:?'Fiscal cliff' 101: 5 basic questions answered

Fifty-three percent of those surveyed in a new CNN/ORC International poll say they view the policies of the GOP as too extreme, up 17 points from two years ago. Only 37 percent say they view the policies of the Democratic Party as too extreme.

?According to the survey, 53 percent say the GOP should compromise more, with 41 percent saying the Democratic Party should give up more of the proposals it supports to develop bipartisan solutions,? CNN reports

"That's due in part to the fact that the Republican brand is not doing all that well," says CNN Polling Director Keating Holland.

This same survey shows just 34 percent feeling good about the job Boehner is doing ? 18 points lower than Obama?s job approval rating.

"Small wonder that nearly half say they have more confidence in President Obama than in the congressional Republicans and that nearly half (48 percent) would blame the GOP if the fiscal cliff occurs," says Mr. Holland.

(Thirty-seven percent said they would blame the president more, with 11 percent saying they would blame both sides equally if they don?t find a way to avoid the fiscal cliff.)

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/1LZxXPiukvc/In-fiscal-cliff-fight-Obama-gets-better-marks-than-Boehner

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